North Clayton Vacations from $244
Book a Hotel + Flight or Car together to unlock savings
Your North Clayton Vacation
Discover all the amazing things this neighborhood has to offer with a tailor-made North Clayton vacation package. However you imagine yourself spending your time here, you'll find endless opportunities for relaxation, fun and adventure. Wondering what to see and do during your trip to North Clayton? Nearby attractions like St. Louis Zoo, St. Louis Art Museum and Washington University in St. Louis are good places to begin. Expedia will help turn your ideal North Clayton vacation into reality, whatever your travel plans or budget.
The Latest North Clayton Vacation Packages
Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel
Save 100% on your flight
Price was $438, price is now $244 per person
$244
per person
Sep 3 - Sep 5
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,663 reviews)
The employees were nice, friendly and helpful. The room was roomy, clean and the bed was nice and comfortable. I really like that the B&B Theater was right across the street to walk to. We enjoyed a movie at the Theater.
Reviewed on Jul 1, 2026
Moonrise Hotel
Delmar Loop
Save 100% on your flight
Price was $414, price is now $287 per person
$287
per person
Aug 1 - Aug 4
found 20 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9/10 Wonderful! (1,976 reviews)
Beware if your room is on the 7th floor. The rooftop bar directly above is loud. as. hell. for. HOURS.
Reviewed on Jul 1, 2026
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
Save 100% on your flight
Price was $413, price is now $309 per person
$309
per person
Aug 1 - Aug 4
found 20 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,058 reviews)
Beautiful rooms
Reviewed on Jun 30, 2026
Where to stay in North Clayton
Find the best North Clayton areas and neighborhoods for the activities you enjoy most. Learn more about North Clayton
Downtown St. Louis
3 out of top 10 points of interest in this area
4/5(4,044 area reviews)
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.
North Clayton Hotel Deals
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
216 N Meramec Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $154 total per night from Jul 5 to Jul 6
$154 total
Jul 5 - Jul 6
Total with taxes and fees
8.8/10 Excellent! (1,000 reviews)
"The rooms are getting a little dated. The bathroom did not have a fans so it was humid after a shower. The rooms were very dark."
Reviewed on Jun 29, 2026
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $165 total per night from Jul 17 to Jul 18
$165 total
Jul 17 - Jul 18
Total with taxes and fees
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $112 total per night from Jul 12 to Jul 13
$112 total
Jul 12 - Jul 13
Total with taxes and fees
8.8/10 Excellent! (3,252 reviews)
"The main parking garage was down so we had to park somewhere else which wasn’t convenient at all. They want to hold $100 for any damages that may occur while you’re staying there. The first night out we had to get a different room due to the refrigerator not working and the pull out couch was broke ..."
Reviewed on Jul 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
$24
per adult
100% of travellers recommend
St. Louis Premium Small Group Tour With Arch & River Cruise
$161
per adult
84% of travellers recommend
Picnic for 2 in Forest Park: 4 Iconic Eateries in Every Basket!
$159
per traveler
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.